Redefining massive transfusion
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چکیده
منابع مشابه
Redefining massive transfusion
Background The concept of massive transfusion was developed to trigger clotting factor therapy for the treatment of coagulopathy due to dilution, after a certain number of units of packed red blood cells. It has been defined as the replacement of circulating volume or the transfusion of more than 6 or 10 units of packed red blood cells (PRBC) in the 24 hours after injury. Until recently there h...
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Massive Transfusion is a part of Damage Control Resuscitation. The aim of transfusion therapy is to restore oxygen delivery to poorly perfused tissues and to treat the acute coagulopathy of trauma. The severity and complexity of modern injuries have led to the use of swift, protocol-driven care with the use of'Shock Packs' and management of metabolic complications. The proactive treatment of th...
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Massive bleeding in trauma patients is a serious challenge for all clinicians, and an interdisciplinary diagnostic and therapeutic approach is warranted within a limited time frame. Massive transfusion usually is defined as the transfusion of more than 10 units of packed red blood cells (RBCs) within 24 h or a corresponding blood loss of more than 1- to 1.5-fold of the body's entire blood volum...
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5 Maintain plasma colloid osmotic pressure "Massive transfusion" is arbitrarily defined as the replacement of the patient's total blood volume by stored homologous bank blood in less than 24 hours. It is a medical emergency, usually occurring in the accident department, the operating theatre, or the obstetric department, when a patient presents with overwhelming haemorrhage and acute hypovolaem...
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Surgical patients requiring massive blood transfusion therapy present many challenges for the anesthetist. The decision to transfuse homologous banked blood and its components must be weighed against the potential complications that may occur in this form of therapy. A review of metabolic changes that occur in banked blood, the risk of infection, and physiologic derangements that may develop du...
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ژورنال
عنوان ژورنال: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
سال: 2009
ISSN: 1757-7241
DOI: 10.1186/1757-7241-17-s1-o1